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High body temperature increases resistance to

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Viral infections affect the elderly more frequently than the younger population. Moreover, elderly individuals also have lower mean body temperatures. Taking cues from these clinical observations, a team of researchers from The University of Tokyo undertook a study to find the missing link between body temperature and infection resistance. Findings indicate that increased body temperature suppresses virus replication and excessive inflammatory responses.

Newborn piglets serve as a model for studying influenza

東京大学医科学研究所 一戸研究室

High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection

Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses

Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses

THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO

THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO

Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses

THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO

THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO

東京大学医科学研究所 一戸研究室